DAD1 antibody

Catalog No. ABIN6568449

This anti-DAD1 antibody is a Rabbit Polyclonal antibody detecting DAD1 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for DAD1 antibody (ABIN6568449)

Target: DAD1 (Defender Against Cell Death 1 (DAD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DAD1 Antibody

Purification: Affinity purification

Immunogen: A synthetic peptide of human DAD1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DAD1

Target: DAD1 (Defender Against Cell Death 1 (DAD1))

Alternative Name: DAD1

Background:

Synonyms: DAD 1,DAD-1,dad1,DAD1,Defender against cell death 1,Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit DAD1,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1,Oligosaccharyl transferase subunit DAD1,OST 2,OST2

Background: DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes.

Molecular Weight:

Observed_MW: 22kDa

Calculated_MW: 12kDa

Gene ID: 1603

UniProt: P61803