COL5A1 antibody

Catalog No. ABIN6568592

Product Details anti-COL5A1 Antibody

Target: COL5A1 (Collagen, Type V, alpha 1 (COL5A1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL5A1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: A synthetic peptide of human COL5A1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COL5A1

Target: COL5A1 (Collagen, Type V, alpha 1 (COL5A1))

Alternative Name: COL5A1 (COL5A1 Products)

Background:

Synonyms: alpha 1 type V collagen,COL5A1,Collagen alpha-1(V) chain,Collagen V

Background: This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. The encoded procollagen protein occurs commonly as the heterotrimer pro-alpha1(V)-pro-alpha1(V)-pro-alpha2(V). Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. Alternative splicing of this gene results in multiple transcript variants.

Molecular Weight:

Observed_MW: 180kDa

Calculated_MW: 183kDa

Gene ID: 1289

UniProt: P20908

Pathways: Growth Factor Binding