ORC3 antibody

Catalog No. ABIN6568693

The Rabbit Polyclonal anti-ORC3 antibody has been validated for WB. It is suitable to detect ORC3 in samples from Human and Mouse.

Quick Overview for ORC3 antibody (ABIN6568693)

Target: ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ORC3 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human ORC3

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ORC3

Target: ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))

Alternative Name: ORC3

Background:

Synonyms: Homolog of latheo Drosophila,LAT,LATHEO,orc3,ORC3,ORC3L,Origin recognition complex subunit 3,Origin recognition complex subunit 3 honolog,Origin recognition complex subunit Latheo

Background: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.

Molecular Weight:

Observed_MW: 82kDa

Calculated_MW: 65kDa/82kDa

Gene ID: 23595

UniProt: Q9UBD5

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Feeding Behaviour, Synthesis of DNA