RBPJ antibody (Recombination Signal Binding Protein For Immunoglobulin kappa J Region)

Details for Product anti-RBPJ Antibody No. ABIN6570040
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
105
42
36
6
5
3
3
3
3
2
1
1
1
1
Host
Rabbit
90
10
4
2
Clonality
Polyclonal
Conjugate
This RBPJ antibody is un-conjugated
6
4
4
3
3
3
3
3
3
2
2
2
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
77
37
36
13
12
9
6
5
3
3
2
2
2
2
1
Options
Immunogen Recombinant protein of human RBPJ
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name RBPJ (RBPJ Antibody Abstract)
Background

Synonyms: AI843960,AOS3,CBF 1,CBF-1,CBF1,csl,IGKJRB,IGKJRB1,J kappa recombination signal binding protein,J kappa-recombination signal-binding protein,KBF2,NY REN 30 antigen,RBP J,RBP J kappa,RBP JK,RBP-J,RBP-J kappa,RBP-JK,Rbpj,RBPJK,RBPSUH,recombination signal binding protein for immunoglobulin kappa J region,Recombining binding protein suppressor of hairless,Renal carcinoma antigen NY-REN-30,SUH,SUH

Background: The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.

Molecular Weight

Observed_MW: 55kDa

Calculated_MW: 45kDa/47kDa/51kDa/54kDa/55kDa

Gene ID 3516
UniProt Q06330
Pathways Notch Signaling, Stem Cell Maintenance, Smooth Muscle Cell Migration
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:50
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) antibody (ABIN6570040) Immunofluorescence analysis of MCF-7 cells using RBPJ antibody.
Image no. 2 for anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) antibody (ABIN6570040) Western blot analysis of extracts of mouse lung, using RBPJ antibody.
Image no. 3 for anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) antibody (ABIN6570040) Immunohistochemistry of paraffin-embedded human stomach using RBPJ Antibody.