RBPJ antibody
-
- Target See all RBPJ Antibodies
- RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This RBPJ antibody is un-conjugated
-
Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human RBPJ (NP_976028.1).
- Isotype
- IgG
- Top Product
- Discover our top product RBPJ Primary Antibody
-
-
- Application Notes
- IHC 1:50-1:200 IF 1:20-1:50
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
- Alternative Name
- RBPJ (RBPJ Products)
- Synonyms
- AOS3 antibody, CBF1 antibody, IGKJRB antibody, IGKJRB1 antibody, KBF2 antibody, RBP-J antibody, RBPJK antibody, RBPSUH antibody, SUH antibody, csl antibody, AI843960 antibody, Igkjrb antibody, Igkrsbp antibody, RBP-J kappa antibody, RBPjk antibody, Rbpsuh antibody, Su(H) antibody, XSu(H) antibody, xsu(h)1 antibody, Su(H)1 antibody, Su(h)A antibody, ik:tdsubc_1e8 antibody, rbpj antibody, rbpsuh antibody, xx:tdsubc_1e8 antibody, Su(H)2 antibody, su(h)B antibody, recombination signal binding protein for immunoglobulin kappa J region antibody, recombination signal binding protein for immunoglobulin kappa J region S homeolog antibody, recombination signal binding protein for immunoglobulin kappa J region a antibody, recombination signal binding protein for immunoglobulin kappa J region b antibody, RBPJ antibody, Rbpj antibody, rbpj.S antibody, rbpja antibody, rbpjb antibody
- Background
- The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.
- Molecular Weight
-
Observed_MW: 55kDa
Calculated_MW: 45kDa/47kDa/51kDa/54kDa/55kDa
- Gene ID
- 3516
- UniProt
- Q06330
- Pathways
- Notch Signaling, Stem Cell Maintenance, Smooth Muscle Cell Migration
-