YARS antibody

Catalog No. ABIN6570715

Product Details anti-YARS Antibody

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YARS antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purification: Affinity purification

Immunogen: Recombinant protein of human YARS

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IP 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for YARS

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Alternative Name: YARS (Yars Products)

Background:

Synonyms: CMTDIC,SYYC,Tyrosine tRNA ligase,cytoplasmic,Tyrosine tRNA ligase 1,cytoplasmic,Tyrosyl tRNA synthetase,Tyrosyl--tRNA ligase,Tyrosyl-tRNA synthetase,cytoplasmic,TyrRS,yars,YRS,YTS

Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.

Molecular Weight:

Observed_MW: 59kDa

Calculated_MW: 59kDa

Gene ID: 8565

UniProt: P54577