GNB1L antibody

Catalog No. ABIN6571380

The Rabbit Polyclonal anti-GNB1L antibody has been validated for WB. It is suitable to detect GNB1L in samples from Human, Mouse and Rat.

Quick Overview for GNB1L antibody (ABIN6571380)

Target: GNB1L (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1-Like (GNB1L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNB1L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GNB1L Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human GNB1L

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GNB1L

Target: GNB1L (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1-Like (GNB1L))

Alternative Name: GNB1L

Background:

Synonyms: DGCRK3,ESTM55 ,fb98e06,fj09d12,FKSG1,G protein subunit beta-like protein 1,G-protein beta subunit-like protein,GNB1L,GNB1L,guanine nucleotide binding protein (G protein), beta polypeptide 1-like,guanine nucleotide binding protein beta-subunit-like polypeptide,Guanine nucleotide-binding protein subunit beta-like protein 1,GY2,KIAA1645,WD repeat-containing protein 14,WD40 repeat-containing protein deleted in VCFS,WDR14,WDVCF,wu:fb98e06,wu:fj09d12 ,zgc:55774

Background: This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders. Transcripts from this gene share exons with some transcripts from the C22orf29 gene.

Molecular Weight:

Observed_MW: 36kDa

Calculated_MW: 22kDa/35kDa

Gene ID: 54584

UniProt: Q9BYB4