SUPT5H antibody

Catalog No. ABIN6571954

This anti-SUPT5H antibody is a Rabbit Polyclonal antibody detecting SUPT5H in WB. Suitable for Human and Mouse.

Quick Overview for SUPT5H antibody (ABIN6571954)

Target: SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUPT5H antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SUPT5H Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human SUPT5H

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SUPT5H

Target: SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))

Alternative Name: SUPT5H

Background:

Synonyms: DRB sensitivity inducing factor large subunit,DRB sensitivity-inducing factor 160 kDa subunit,DRB sensitivity-inducing factor large subunit,DSIF large subunit,DSIF p160,FLJ34157,hSPT 5,hSPT5,SPT 5,SPT 5H,SPT5,SPT5H,SPT5H,Suppressor of Ty 5 homolog ,Suppressor of Ty 5 homolog (S. cerevisiae),SUPT 5H,supt5h,Tat cotransactivator 1 protein,Tat CT1,Tat CT1 protein,Tat-cotransactivator 1 protein,Tat-CT1 protein,Transcription elongation factor SPT 5,Transcription elongation factor spt5,Transcription factor Tat CT1

Background: SUPT5H, also named as DSIF p160, is a 1087 amino acid protein, which belongs to the SPT5 family. SUPT5H localizes in the nucleus and is ubiquitously expressed. SUPT5H is a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. SUPT5H is modified through phosphorylation and methylated, so the molecular weight of SUPT5H might be 140-150 kDa.

Molecular Weight:

Observed_MW: 170kDa

Calculated_MW: 120kDa/121kDa

Gene ID: 6829

UniProt: O00267