OPA1 antibody

Catalog No. ABIN6572036

This anti-OPA1 antibody is a Rabbit Polyclonal antibody detecting OPA1 in WB. Suitable for Human, Rat and Mouse.

Quick Overview for OPA1 antibody (ABIN6572036)

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OPA1 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human OPA1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OPA1

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Alternative Name: OPA1

Background:

Synonyms: Dynamin like 120 kDa protein,Dynamin like 120 kDa protein, mitochondrial,Dynamin-like 120 kDa protein, form S1,FLJ12460,Juvenile kjer type optic atrophy,KIAA0567,KJER type,Large GTP binding protein,largeG,MGM1,Mitochondrial dynamin like 120 kDa protein,Mitochondrial dynamin like GTPase,NPG,NTG,OAK,OPA 1,opa1,OPA1 gene,OPA1,Optic atrophy 1 (autosomal dominant),OPTIC ATROPHY 1,Optic atrophy 1 gene protein,Optic atrophy 1 homolog (human),Optic atrophy protein 1,Optic atrophy protein 1 homolog

Background: This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 112kDa

Calculated_MW: 111kDa/115kDa

Gene ID: 4976

UniProt: O60313

Pathways: Tube Formation