NLRP10 antibody (C-Term)

Catalog No. ABIN657417

Product Details anti-NLRP10 Antibody

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Binding Specificity: AA 466-494, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP10 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NLRP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 466-494 amino acids from the C-terminal region of human NLRP10.

Clone: RB33404

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: NLRP10 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for NLRP10

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Alternative Name: NLRP10 (NLRP10 Products)

Background: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq].

Molecular Weight: 75032

Gene ID: 338322

NCBI Accession: NP_789791

UniProt: Q86W26

Pathways: Inflammasome