Histone H4 antibody (acLys12)

Catalog No. ABIN6579166

This anti-Histone H4 antibody is a Rabbit Polyclonal antibody detecting Histone H4 in WB, IF, ChIP, DB, ICC and ChIP-seq. Suitable for Human, Mouse and Saccharomyces cerevisiae. This Primary Antibody has been cited in 7+ publications.

Quick Overview for Histone H4 antibody (acLys12) (ABIN6579166)

Target: Histone H4

Reactivity: Human, Mouse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB), Immunocytochemistry (ICC), ChIP DNA-Sequencing (ChIP-seq)

Product Details anti-Histone H4 Antibody

Binding Specificity: acLys12

Purification: None

Immunogen: This Histone H4 acetylLys12 antibody was raised against a peptide including acetyllysine 12 of histone H4.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-Histone H4 antibody (ABIN6579166)

Meers, Henriques, Lavender, McKay, Strahl, Duronio, Adelman, Matera: "Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity." in: eLife, Vol. 6, (2017) (PubMed).

Johnson, French, Osheim, Li, Hall, Beyer, Smith: "Rpd3- and spt16-mediated nucleosome assembly and transcriptional regulation on yeast ribosomal DNA genes." in: Molecular and cellular biology, Vol. 33, Issue 14, pp. 2748-59, (2013) (PubMed).

Wan, Hu, Liu, Han, Sood, Calin, Zhang, Lu: "A novel non-coding RNA lncRNA-JADE connects DNA damage signalling to histone H4 acetylation." in: The EMBO journal, Vol. 32, Issue 21, pp. 2833-47, (2013) (PubMed).

Larsson, Ulfhammer, Magnusson, Bergh, Lunke, El-Osta, Medcalf, Svensson, Karlsson, Jern: "Role of histone acetylation in the stimulatory effect of valproic acid on vascular endothelial tissue-type plasminogen activator expression." in: PLoS ONE, Vol. 7, Issue 2, pp. e31573, (2012) (PubMed).

Liu, McConnell, Dixon, Calvi: "Analysis of model replication origins in Drosophila reveals new aspects of the chromatin landscape and its relationship to origin activity and the prereplicative complex." in: Molecular biology of the cell, Vol. 23, Issue 1, pp. 200-12, (2012) (PubMed).

Silva, Xu, Kim, Fillingham, Kislinger, Mennella, Keogh: "The replication-independent histone H3-H4 chaperones HIR, ASF1, and RTT106 co-operate to maintain promoter fidelity." in: The Journal of biological chemistry, Vol. 287, Issue 3, pp. 1709-18, (2012) (PubMed).

Li, Corsa, Pan, Wu, Ferguson, Yu, Min, Dou: "MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1." in: Molecular and cellular biology, Vol. 30, Issue 22, pp. 5335-47, (2010) (PubMed).

Target Details for Histone H4

Target: Histone H4

Molecular Weight: 8 kDa

Gene ID: 121504