Arylsulfatase A antibody

Catalog No. ABIN6654013

The Mouse Monoclonal anti-Arylsulfatase A antibody has been validated for WB and FACS. It is suitable to detect Arylsulfatase A in samples from Human, Mouse and Rat.

Quick Overview for Arylsulfatase A antibody (ABIN6654013)

Target: Arylsulfatase A (ARSA)

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Arylsulfatase A antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 4C10

Product Details anti-Arylsulfatase A Antibody

Purification: Protein G affinity

Immunogen: Amino acids QALKQLQLLKAQLDAAVTFGPSQVARGED were used as the immunogen for the ARSA antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the ARSA antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Flow Cytometry: 1-3 μg/10^6 cells

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the ARSA antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Arylsulfatase A

Target: Arylsulfatase A (ARSA)

Alternative Name: ARSA

Background: Arylsulfatase A (ARSA) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate intocerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene. ARSA is mapped to 22q13.33. The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

UniProt: P15289