CST3 antibody (AA 21-140)

Catalog No. ABIN6654029

This anti-CST3 antibody is a Rabbit Polyclonal antibody detecting CST3 in WB and ELISA. Suitable for Mouse.

Quick Overview for CST3 antibody (AA 21-140) (ABIN6654029)

Target: CST3 (Cystatin C (CST3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CST3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CST3 Antibody

Binding Specificity: AA 21-140

Purification: Antigen affinity purified

Immunogen: Mouse Cystatin C recombinant protein (amino acids A21-A140) was used as the immunogen for the Cystatin C antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Cystatin C antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,ELISA (capture): 1-5 μg/mL (mouse recombinant protein)

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Cystatin C antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for CST3

Target: CST3 (Cystatin C (CST3))

Alternative Name: Cystatin C / Cystatin 3

Background: Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.

UniProt: P21460