PLA2G7 antibody (AA 176-415)

Catalog No. ABIN6654171

This Rabbit Polyclonal antibody specifically detects PLA2G7 in WB and ELISA (Capture). It exhibits reactivity toward Human.

Quick Overview for PLA2G7 antibody (AA 176-415) (ABIN6654171)

Target: PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA (Capture)

Product Details anti-PLA2G7 Antibody

Binding Specificity: AA 176-415

Purification: Antigen affinity purified

Immunogen: Amino acids A176-N415 from the human protein were used as the immunogen for the PLA2G7 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PLA2G7 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,ELISA (Capture): 1-5 μg/mL (human recombinant protein)

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the PLA2G7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for PLA2G7

Target: PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))

Alternative Name: PLA2G7 / Lp-PLA2 / PAFAH

Background: Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet-activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme that in humans is encoded by the PLA2G7 gene. Lp-PLA2 is a 45-50 kDa protein of 441 amino acids. It is one of several PAF acetylhydrolases. In the blood it travels mainly with low-density lipoprotein (LDL). Less than 20 % is associated with high-density lipoprotein HDL. It is an enzyme produced by inflammatory cells and hydrolyzes oxidized phospholipids in LDL. Lp-PLA2 is platelet-activating factor (PAF) acetylhydrolase, a secreted enzyme that catalyzes the degradation of PAF to inactive products by hydrolysis of the acetyl group at the sn-2 position, producing the biologically inactive products LYSO-PAF and acetate.

UniProt: Q13093

Pathways: Peptide Hormone Metabolism