GATA3 antibody (AA 357-463)

Catalog No. ABIN6654536

This anti-GATA3 antibody is a Mouse Monoclonal antibody detecting GATA3 in IHC (p). Suitable for Human.

Quick Overview for GATA3 antibody (AA 357-463) (ABIN6654536)

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GATA3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GATA3-2442

Product Details anti-GATA3 Antibody

Binding Specificity: AA 357-463

Purification: Purified

Purity: Protein G affinity chromatography

Immunogen: A portion of amino acids 357-463 from the human protein were used as the immunogen for this GATA3 antibody.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal dilution of the GATA3 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the GATA3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for GATA3

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Alternative Name: GATA3

Background: GATA3 is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. GATA3 expression is primarily seen in breast and urothelial carcinomas. Therefore, GATA3 antibody can be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility.

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation