PROX1 antibody

Catalog No. ABIN6656043

Supplier Product No.: 200-301-e18

Product Details anti-PROX1 Antibody

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PROX1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Supplier Product No.: 200-301-e18

Supplier: Rockland

Purpose: PROX1 Antibody

Cross-Reactivity (Details): Anti-Prox1 is directed against human Prox1 protein.

Purification: This antibody is Protein G purified from cell culture supernatant.

Immunogen: Anti-Prox 1 Monoclonal Antibody was produced in mouse by repeated immunizations with recombinant human Prox1 protein.

Clone: 5G10

Isotype: IgG1

Application Details

Application Notes: Optional[Neutralization_Dilution]: 1:1000

Comment:

Anti-Prox1 (Mouse) antibody has been tested by IHC. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Preservative: None

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  Aliquot contents and freeze at -20° C or below for extended storage.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for PROX1

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Alternative Name: Prox1 (PROX1 Products)

Background:

Synonyms: Prospero homeobox protein 1, Homeobox prospero-like protein PROX1

Background: Prox1 (Prospero-related homeobox 1) is a divergent homeogene that regulates cell proliferation, fate determination and differentiation during vertebrate embryonic development. The protein is expressed in the developing lens and is also detected in embryonic brain, lung, liver and kidney, while in adult it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas. Prox1 is thought to play a fundamental role in early development of the CNS and may regulate gene expression and development of postmitotic undifferentiated young neurons. Anti-Prox1 Monoclonal Antibody is suitable for investigators involved in Cell Signaling, Neuroscience, and Signal Transduction research.

Gene Name: PROX1

Gene ID: 5629

UniProt: Q92786

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation