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PROX1 Products

(Prospero Homeobox 1 (PROX1))
The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012].

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Featured PROX1 Categories

PROX1 Antibodies

High quality antibodies with extensive validation data.

PROX1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PROX1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PROX1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (6)
Cat. No. ABIN519306
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS
Validations
  • (6)
Cat. No. ABIN3032345
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IF
Validations
  • (6)
Cat. No. ABIN3032348
Quantity 0.4 mL
Datasheet Datasheet

Recommended PROX1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1150261
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1150262
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1150260
Quantity 96 tests
Datasheet Datasheet

Recommended PROX1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124604
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124605
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316377
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PROX1 products

Gong, Lugo-Cintron, White, Kerr, Harari, Beebe: "Human organotypic lymphatic vessel model elucidates microenvironment-dependent signaling and barrier function." in: Biomaterials, Vol. 214, pp. 119225, (2019) (PubMed).

Shibata-Germanos, Goodman, Grieg, Trivedi, Benson, Foti, Faro, Castellan, Correra, Barber, Ruhrberg, Weller, Lashley, Iliff, Hawkins, Rihel: "Structural and functional conservation of non-lumenized lymphatic endothelial cells in the mammalian leptomeninges." in: Acta neuropathologica, (2019) (PubMed).

Redondo, Gubert, Zaverucha-do-Valle, Dutra, Ayres-Silva, Fernandes, de Souza, Loizidou, Takiya, Rossi, Borojevic: "Lymphatic vessels in human adipose tissue." in: Cell and tissue research, (2019) (PubMed).

Yang, Gao, Ma, Teng, Liu, Wei, Lu, Cheng, Hou, Zou: "Fucoidan inhibits lymphangiogenesis by downregulating the expression of VEGFR3 and PROX1 in human lymphatic endothelial cells." in: Oncotarget, Vol. 7, Issue 25, pp. 38025-38035, (2018) (PubMed).

Park, Cho, Park, Kim, Park, Myung, Lee, Kweon, Joo: "Prospero homeobox 1 mediates the progression of gastric cancer by inducing tumor cell proliferation and lymphangiogenesis." in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, Vol. 20, Issue 1, pp. 104-115, (2017) (PubMed).

Lee, Koh: "Coordinated lymphangiogenesis is critical in lymph node development and maturation." in: Developmental dynamics : an official publication of the American Association of Anatomists, (2016) (PubMed).

Abdolazimi, Stojanova, Segil: "Selection of cell fate in the organ of Corti involves the integration of Hes/Hey signaling at the Atoh1 promoter." in: Development (Cambridge, England), Vol. 143, Issue 5, pp. 841-50, (2016) (PubMed).

Rainey, Ng, Llamas, van der Horst, Segil: "Mutations in Cockayne Syndrome-Associated Genes (Csa and Csb) Predispose to Cisplatin-Induced Hearing Loss in Mice." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 36, Issue 17, pp. 4758-70, (2016) (PubMed).

Park, Myung, Park, Kim, Oak, Myung, Cho, Lee, Kweon, Kim, Joo: "Impact of prospero homeobox-1 on tumor cell behavior and prognosis in colorectal cancer." in: American journal of cancer research, Vol. 5, Issue 11, pp. 3286-300, (2016) (PubMed).

Zhang, Brady, Liang, Wu, Henkemeyer, Yan: "EphB4 forward signalling regulates lymphatic valve development." in: Nature communications, Vol. 6, pp. 6625, (2016) (PubMed).

Synonyms and alternative names related to PROX1

prospero homeobox 1 (PROX1), prospero homeobox 1 L homeolog (prox1.L), prospero homeobox 1 (prox1), prospero homeobox 1 (Prox1), prospero homeobox 1a (prox1a), A230003G05Rik, LOC100232600, prospero, PROX1, prox1, xprox1, zgc:111888

Protein level used designations for PROX1

  • prospero homeobox 1
  • prospero homeobox protein 1-like
  • Prox 1
  • prospero-related homeobox 1
  • homeobox prospero-like protein PROX1
  • prospero homeobox protein 1
  • PROX-1
  • prospero-related homeobox gene 1
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