STX1A antibody

Catalog No. ABIN6657443

Supplier Product No.: 200-301-e40

This anti-STX1A antibody is a Mouse Monoclonal antibody detecting STX1A in WB and IHC. Suitable for Human.

Quick Overview for STX1A antibody (ABIN6657443)

Target: STX1A (Syntaxin 1A (Brain) (STX1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This STX1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: SP8

Product Details anti-STX1A Antibody

Supplier Product No.: 200-301-e40

Supplier: Rockland

Purpose: Syntaxin Antibody

Cross-Reactivity (Details): Anti-Syntaxin Monoclonal Antibody is directed against Syntaxin.

Purification: Syntaxin antibody was purified by Protein G chromatography from cell culture supernatant.

Immunogen: Anti-Syntaxin Monoclonal Antibody was produced in mouse by repeated immunizations with Synaptic immunoprecipitate (crude) from human brain.

Isotype: IgG1

Application Details

Application Notes:

Immunohistochemistry_Dilution: 1:100

Western_Blot_Dilution: 1:1000

Comment:

Anti-Syntaxin antibody is suitable for use in Western Blotting and IHC. Expect a band or approximately 36 kDa in size corresponding to syntaxin proteins in Western blot of rat brain lysate. Tested for use in immunohistochemistry on formalin fixed, vibratome sections. Does not work on paraffin sections. Researchers should determine optimal titers for applications that are not stated below.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for STX1A

Target: STX1A (Syntaxin 1A (Brain) (STX1A))

Alternative Name: STX1A

Background:

Synonyms: Neuron-specific antigen HPC-1, Syntaxin-1A

Background: Syntaxin antibody detects Syntaxin-1A protein which is part of a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion. Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have recently been correlated with schizophrenia. Anti-Syntaxin Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: STX1A

Gene ID: 6804

UniProt: Q16623

Pathways: Peptide Hormone Metabolism, Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport