Glucagon antibody

Catalog No. ABIN6657488

Supplier Product No.: 200-301-p38

This anti-Glucagon antibody is a Mouse Monoclonal antibody detecting Glucagon in IHC. Suitable for Pig.

Quick Overview for Glucagon antibody (ABIN6657488)

Target: Glucagon (GCG)

Reactivity: Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This Glucagon antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: K79bB10

Product Details anti-Glucagon Antibody

Supplier Product No.: 200-301-p38

Supplier: Rockland

Purpose: Glucagon Antibody

Cross-Reactivity (Details): This product reacts with human, mouse, rat, and rabbit.

Purification: Anti-Glucagon antibody was purified from mouse ascites by protein A chromatography.

Immunogen: Glucagon antibody was produced in mice by repeated immunizations with polymerized porcine glucagon.

Isotype: IgG1

Application Details

Application Notes: Optional[Neutralization_Dilution]: 1:100-1:500

Comment:

Anti-Glucagon is tested for Immunohistochemistry -P. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~20.9 kDa corresponding to the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Neutral PBS

Reconstitution_Volume: 1.0 mL

Buffer:

Buffer: 1.2 % sodium acetate

Stabilizer: 2 mg BSA

Preservative: 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for Glucagon

Target: Glucagon (GCG)

Alternative Name: Glucagon

Background:

Synonyms: GLP1, GLP2, glicentin-related polypeptide, glucagon-like peptide 1, glucagon-like peptide 2

Background: Glucagon is a member of a multigene family that includes secretin. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. the human glucagon gene is approximately 9.4 kb long and contains 6 exons and 5 introns, and assigned to 2q36-2q37. This antibody is suitable for researchers interested in cancer research, metabolic diseases, transcription factors and nuclear receptors, neuroscience research, SKT signaling, GCPR signaling, and calcium signaling research.

Gene Name: GCG

Gene ID: 397595

NCBI Accession: NP_999489

UniProt: P01274

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling