GAP43 antibody (C-Term)

Catalog No. ABIN6658062

Supplier Product No.: 200-901-x10

This Chicken Polyclonal antibody specifically detects GAP43 in WB, IHC and ELISA. It exhibits reactivity toward Rat.

Quick Overview for GAP43 antibody (C-Term) (ABIN6658062)

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Reactivity: Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This GAP43 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-GAP43 Antibody

Binding Specificity: C-Term

Supplier Product No.: 200-901-x10

Supplier: Rockland

Purpose: GAP43 Antibody

Purification: Anti-GAP-43 Antibody is a purified total IgY fraction.

Sterility: Sterile filtered

Immunogen: Anti-GAP-43 Antibody was produced in chickens by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the C-terminal region of rat GAP43 conjugated to KLH.

Isotype: IgG

Application Details

Application Notes:

ELISA_Dilution: 1:20,000

Immunohistochemistry_Dilution: 1:500-1:2000

Western_Blot_Dilution: 1:2000

Other: ICC: 1:500-1:2000

Comment:

Anti-GAP-43 Antibody is tested for Western Blot, immunohistochemistry, and immunocytochemistry, and it is specific for the ~43k GAP-43 protein. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.1 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.

Expiry Date: 12 months

Target Details for GAP43

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Alternative Name: GAP-43

Background:

Synonyms: Neuromodulin, Axonal membrane protein GAP-43, Growth-associated protein 43, Protein F1

Background: GAP-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. There is also evidence from knockout animals that GAP-43 serves to amplify pathfinding signals from the growth cone. GAP-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser41 by protein kinase C modulates the interaction of GAP-43 with actin and may also affect neurotransmitter release during forms of plasticity like LTP. GAP-43 Antibody is ideal for researchers interested in neuroscience research.

Gene Name: GAP43

Gene ID: 29423

NCBI Accession: NP_058891

UniProt: P07936