KCNC1 antibody (pSer503)

Catalog No. ABIN6658160

Supplier Product No.: 600-401-e14

Product Details anti-KCNC1 Antibody

Target: KCNC1 (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 (KCNC1))

Binding Specificity: pSer503

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Supplier Product No.: 600-401-e14

Supplier: Rockland

Purpose: Potassium Channel, Voltage-Gated, Kv3.1 phospho S503 Antibody

Purification: Anti-Potassium Channel, Voltage Gated Kv2.2 pS5003 Antibody is directed against phosphorylated rat Voltage Gated Potassium Channel Kv2.

Immunogen: Anti-Potassium Channel, Voltage-Gated Kv3.1 pS503 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser503.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry_Dilution: 1:1000

Western_Blot_Dilution: 1:1000

Other: User Optimized

Comment:

Anti-Potassium Channel, Voltage-Gated Kv3.1 pS503 Antibody is tested for use in Western Blotting and IHC. Expect a band of approximately 100kDa in size corresponding to Kv3.1 voltage-gated potassium channel protein phosphorylated at Ser503 in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for KCNC1

Target: KCNC1 (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 1 (KCNC1))

Alternative Name: Kcnc1 (KCNC1 Products)

Background:

Synonyms: Potassium voltage-gated channel subfamily C member 1, NGK2, RAW2, Voltage-gated potassium channel subunit Kv4

Background: Potassium Channel, Voltage Gated Kv2.2 pS503 Antibody detects Voltage Gated Potassium Channel Kv2.2 pS503 protein. Voltage-gated K+ channels are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The Kv3.1 potassium channel is expressed at high levels in neurons that characteristically fire rapid trains of action potentials. Anti-Potassium Channel, Voltage Gated Kv2.2 pS503 Antibody is ideal for investigators involved in Neuroscience and Cell Signaling research.

Gene Name: KCNC1

Gene ID: 25327

UniProt: P25122