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mGluR2/3 antibody (C-Term)

GRIA2/3 Reactivity: Rat WB Host: Rabbit Polyclonal unconjugated
Rockland
Catalog No. ABIN6658279
Supplier Product No.: 612-401-d63
  • Target See all mGluR2/3 (GRIA2/3) products
    mGluR2/3 (GRIA2/3) (Glutamate Receptor, Ionotropic, AMPA 2/3 (GRIA2/3))
    Binding Specificity
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 16
    • 16
    • 13
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Rat
    Host
    • 21
    Rabbit
    Clonality
    • 20
    • 1
    Polyclonal
    Conjugate
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This mGluR2/3 antibody is un-conjugated
    Application
    • 14
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Supplier Product No.
    612-401-d63
    Supplier
    Rockland
    Purpose
    GluR2/3 Antibody
    Cross-Reactivity (Details)
    Anti-GluR2/3 Antibody is directed against rat GluR2/3 protein.
    Purification
    The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
    Immunogen
    Anti-GluR2/3 Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region.
    Isotype
    IgG
  • Application Notes
    Optional[Neutralization_Dilution]: 1:1000
    Comment

    Anti-GluR2/3 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 100 kDa in size corresponding to GluR2/3 protein in the appropriate cell lysate or extract.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    Storage
    4 °C,-20 °C
    Storage Comment
    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
    Expiry Date
    12 months
  • Target
    mGluR2/3 (GRIA2/3) (Glutamate Receptor, Ionotropic, AMPA 2/3 (GRIA2/3))
    Alternative Name
    GluR2/3 (GRIA2/3 Products)
    Background

    Synonyms: Glutamate receptor 2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2

    Background: GluR2/3 Antibody detects GluR2/3 protein. The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory. Therefore, GluR2/3 is ideal for investigators involved in synaptic plasticity study and more in general in Neuroscience.

    Gene Name: GRIA2/3

    Gene ID
    29627
    UniProt
    P19491
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