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Connexin 43/GJA1 antibody (Gap Junction Protein, alpha 1, 43kDa) (AA 211-260) Primary Antibody

GJA1 Reactivity: Human, Mouse, Rat, Dog ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Pubmed (3)
Catalog No. ABIN671451
$339.90
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target
    Connexin 43/GJA1 (GJA1)
    Binding Specificity
    • 25
    • 16
    • 15
    • 13
    • 8
    • 8
    • 8
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 211-260
    Reactivity
    • 145
    • 99
    • 95
    • 35
    • 13
    • 12
    • 10
    • 10
    • 9
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog
    Host
    • 140
    • 10
    • 10
    Rabbit
    Clonality
    • 148
    • 11
    Polyclonal
    Conjugate
    • 94
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Connexin 43/GJA1 antibody is un-conjugated
    Application
    • 110
    • 60
    • 57
    • 31
    • 20
    • 19
    • 12
    • 12
    • 11
    • 10
    • 8
    • 6
    • 2
    • 2
    • 1
    ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Cross-Reactivity
    Chicken, Cow
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Connexin-43
    Isotype
    IgG
  • Application Notes
    WB 1:300-1000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C
    Expiry Date
    12 months
  • Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." in: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, 2014 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Dog (Canine)). Further details: Sample: Heart

    Chen, Gao, Ni, Dai: "Carbenoxolone pretreatment and treatment of posttraumatic epilepsy." in: Neural regeneration research, Vol. 8, Issue 2, pp. 169-76, 2014 (PubMed).

    Gao, Zhang, Ding, Chen, Hu, Jiang, Li, Chen, Wang, Ye, Zhu: "Common expression of stemness molecular markers and early cardiac transcription factors in human Wharton's jelly-derived mesenchymal stem cells and embryonic stem cells." in: Cell transplantation, Vol. 22, Issue 10, pp. 1883-900, 2014 (PubMed). Method employed by authors: Immunofluorescence (Cultured Cells) (IF (cc))

  • Target
    Connexin 43/GJA1 (GJA1)
    Alternative Name
    Connexin 43 (GJA1 Antibody Abstract)
    Synonyms
    AVSD3, CX43, DFNB38, GJAL, HLHS1, HSS, ODDD, Cx43, AU042049, AW546267, Cnx43, Cx43alpha1, Gja-1, Npm1, connexin43, cx43a1, gja1, zfCx43.3, connexin 43, gja1-A, cx43, gjal, oddd, dfnb38, gap junction protein alpha 1, gap junction protein, alpha 1, connexin 43, gap junction protein alpha 1 L homeolog, CONNEXIN 43 protein, GJA1, Gja1, cx43, gja1.L, gja1, CONNEXIN 43
    Background

    Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).

    Subcellular location: Cytoplasm, Cell membrane, Extracellular matrix

    Synonyms: HSS, CMDR, CX43, GJAL, ODDD, AVSD3, HLHS1, Gap junction alpha-1 protein, Connexin-43, Gap junction 43 kDa heart protein, GJA1

    Gene ID
    2697
    UniProt
    P17302
    Pathways
    MAPK Signaling, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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