CD28 antibody (Alexa Fluor 488)

Catalog No. ABIN6724263

This Hamster Monoclonal antibody specifically detects CD28 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for CD28 antibody (Alexa Fluor 488) (ABIN6724263)

Target: CD28

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This CD28 antibody is conjugated to Alexa Fluor 488

Application: Flow Cytometry (FACS)

Clone: 37-51

Product Details anti-CD28 Antibody (Alexa Fluor 488)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD28

Target: CD28

Alternative Name: CD28

Background:

Synonyms: T-cell-specific surface glycoprotein CD28,Cd28,CD28

Background: CD28 is a 44 kD glycoprotein, also known as Tp44 or T44. It is a member of the Ig superfamily, expressed on thymocytes, most peripheral T cells, and NK cells. In association with CD80 (B7-1) and CD86 (B7-2), CD28 acts as the second signal for T and NK cell activation and proliferation. The 37.51 antibody has been reported to augment in vitro T cell proliferation and cytokine production, and promote CTL development.

Gene ID: 12487

UniProt: P31041

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response