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PD-L1 antibody

This anti-PD-L1 antibody is a Rat Monoclonal antibody detecting PD-L1 in FACS. Suitable for Mouse.
Catalog No. ABIN6727404

Quick Overview for PD-L1 antibody (ABIN6727404)

Target

See all PD-L1 Antibodies
PD-L1 (CD274 (PD-L1))

Reactivity

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Mouse

Host

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Rat

Clonality

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Monoclonal

Conjugate

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This PD-L1 antibody is un-conjugated

Application

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Flow Cytometry (FACS)

Clone

10F-9G2
  • Purification

    Purified

    Isotype

    IgG2b, kappa
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Comment

    Matching Isotype Control: Purified Rat IgG2b, κ Isotype Control (ABIN7469856)

    Restrictions

    For Research Use only
  • Concentration

    0.5 mg/mL

    Buffer

    PBS with 0.05 % Proclin300

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    Store at 2~8°C. Do not freeze.
  • Target

    PD-L1 (CD274 (PD-L1))

    Alternative Name

    CD274/PD-L1

    Background

    B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.

    Gene ID

    60533

    UniProt

    Q9EP73

    Pathways

    Cancer Immune Checkpoints
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