Ly6a antibody (Lymphocyte Antigen 6 Complex, Locus A) (PE)

Details for Product anti-Ly6a Antibody No. ABIN6728481
Antigen
  • Ly-6A.2
  • Ly-6A/E
  • Ly-6E.1
  • Sca-1
  • Sca1
  • TAP
  • lymphocyte antigen 6 complex, locus A
  • Ly6a
Reactivity
Mouse (Murine)
125
9
4
Host
Rat
97
32
1
Clonality (Clone)
Monoclonal ()
Conjugate
This Ly6a antibody is conjugated to PE
19
14
14
11
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Flow Cytometry (FACS)
99
46
33
24
8
7
5
1
1
1
Options
Clone D7
Isotype IgG2a, kappa
Plasmids, Primers & others Plasmids, Primers & others Ly6a products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Ly6A/E(Sca-1) (Ly6a Antibody Abstract)
Background

Synonyms: Ly6a,Ly6,Ly-6A.2/Ly-6E.1,SCA-1,TAP

Background: Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

Gene ID 110454
UniProt P05533
Pathways Sensory Perception of Sound, Activated T Cell Proliferation
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS with 0.05 % Proclin300, 1 % BSA
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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