CACNG1 antibody (AA 79-128)

Catalog No. ABIN6746117

This Rabbit Polyclonal antibody specifically detects CACNG1 in WB. It exhibits reactivity toward Mouse, Human, Rat, Rabbit, Guinea Pig, Dog, Bat, Hamster and Monkey and has been mentioned in 4+ publications.

Quick Overview for CACNG1 antibody (AA 79-128) (ABIN6746117)

Target: CACNG1 (Calcium Channel, Voltage-Dependent, gamma Subunit 1 (CACNG1))

Reactivity: Mouse, Human, Rat, Rabbit, Guinea Pig, Dog, Bat, Hamster, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNG1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CACNG1 Antibody

Binding Specificity: AA 79-128

Specificity: Rat CACNG1

Predicted Reactivity: Percent identity by BLAST analysis: Mouse, Rat (100%) Chicken (92%) Dog (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa79-128 of rat Cacng1 (P97707, NP_062128). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Bat, Rabbit, Guinea pig (100%), Bovine, Horse, Opossum, Chicken, Platypus (92%), Elephant, Dog, Turkey, Zebra finch (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-CACNG1 antibody (ABIN6746117)

Takeda, Hatai, Hamazaki, Nishitoh, Saitoh, Ichijo: "Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cells." in: The Journal of biological chemistry, Vol. 275, Issue 13, pp. 9805-13, (2000) (PubMed).

Alonso, Grundke-Iqbal, Iqbal: "Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules." in: Nature medicine, Vol. 2, Issue 7, pp. 783-7, (1996) (PubMed).

Kanai, Hirokawa: "Sorting mechanisms of tau and MAP2 in neurons: suppressed axonal transit of MAP2 and locally regulated microtubule binding." in: Neuron, Vol. 14, Issue 2, pp. 421-32, (1995) (PubMed).

Goedert, Spillantini, Potier, Ulrich, Crowther: "Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain." in: The EMBO journal, Vol. 8, Issue 2, pp. 393-9, (1989) (PubMed).

Target Details for CACNG1

Target: CACNG1 (Calcium Channel, Voltage-Dependent, gamma Subunit 1 (CACNG1))

Alternative Name: CACNG1 / CACNG

Background: Name/Gene ID: CACNG1
Subfamily: Calcium channel - gamma subunit
Family: Ion Channel

Synonyms: CACNG1, CACNG, CACNLG, Gamma 1

Gene ID: 786

NCBI Accession: NP_062128

UniProt: Q06432