LYVE1 antibody (AA 231-318) (Biotin)

Catalog No. ABIN674801

The Rabbit Polyclonal anti-LYVE1 antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect LYVE1 in samples from Human and Mouse.

Quick Overview for LYVE1 antibody (AA 231-318) (Biotin) (ABIN674801)

Target: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LYVE1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LYVE1 Antibody (Biotin)

Binding Specificity: AA 231-318

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse LYVE-1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for LYVE1

Target: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Alternative Name: LYVE-1

Background:

Synonyms: Xlkd1, Lyve-1, Crsbp-1, 1212G8Rik, Lymphatic vessel endothelial hyaluronic acid receptor 1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, Lyve1, Crsbp1

Background: Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Gene ID: 114332

UniProt: Q8BHC0

Pathways: Glycosaminoglycan Metabolic Process