LYVE1 antibody (AA 290-318) (Cy5)

Catalog No. ABIN674803

This Rabbit Polyclonal antibody specifically detects LYVE1 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LYVE1 antibody (AA 290-318) (Cy5) (ABIN674803)

Target: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LYVE1 antibody is conjugated to Cy5

Application: Western Blotting (WB)

Product Details anti-LYVE1 Antibody (Cy5)

Binding Specificity: AA 290-318

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse LYVE-1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LYVE1

Target: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Alternative Name: Lyve-1

Background:

Synonyms: Xlkd1, Lyve-1, Crsbp-1, 1212G8Rik, Lymphatic vessel endothelial hyaluronic acid receptor 1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, Lyve1, Crsbp1

Background: Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Gene ID: 114332

UniProt: Q8BHC0

Pathways: Glycosaminoglycan Metabolic Process