AGTR1a antibody (AA 101-200)

Catalog No. ABIN677873

The Rabbit Polyclonal anti-AGTR1a antibody has been validated for WB, FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) and ICC. It is suitable to detect AGTR1a in samples from Human, Mouse and Rat. There are 2+ publications available.

Quick Overview for AGTR1a antibody (AA 101-200) (ABIN677873)

Target: AGTR1a (Angiotensin II Receptor, Type 1a (AGTR1a))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGTR1a antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-AGTR1a Antibody

Binding Specificity: AA 101-200

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human of human Angiotensin II type 1A receptor

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-AGTR1a antibody (ABIN677873)

Shimizu, Amano, Ito, Betto, Yamane, Inoue, Nishizawa, Matsui, Kamata, Nakamura, Kitasato, Koizumi, Majima: "Angiotensin II subtype 1a receptor signaling in resident hepatic macrophages induces liver metastasis formation." in: Cancer science, Vol. 108, Issue 9, pp. 1757-1768, (2017) (PubMed).

Liu, Liu, Tanabe, Maeda, Zou, Komano: "Differential effects of angiotensin II receptor blockers on A? generation." in: Neuroscience letters, Vol. 567, pp. 51-6, (2014) (PubMed).

Target Details for AGTR1a

Target: AGTR1a (Angiotensin II Receptor, Type 1a (AGTR1a))

Alternative Name: Angiotensin 2 type 1A receptor

Background:

Synonyms: AT1, AG2S, AT1B, AT1R, AT1AR, AT1BR, AT2R1, HAT1R, AGTR1B, Type-1 angiotensin II receptor, Angiotensin II type-1 receptor, AGTR1, AGTR1A, AT2R1B

Background: Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Gene ID: 185

UniProt: P30556

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour