CXCR3 antibody (AA 301-367)

Catalog No. ABIN678653

The Rabbit Polyclonal anti-CXCR3 antibody has been validated for WB. It is suitable to detect CXCR3 in samples from Human, Mouse and Rat. There are 5+ publications available.

Quick Overview for CXCR3 antibody (AA 301-367) (ABIN678653)

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CXCR3 Antibody

Binding Specificity: AA 301-367

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CXCR3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CXCR3 antibody (ABIN678653)

Wang, Tian, Wang, Wei, Wu, Wang, Wang, Yang, Ji, Li: "Anti-inflammatory and retinal protective effects of capsaicin on ischaemia-induced injuries through the release of endogenous somatostatin." in: Clinical and experimental pharmacology & physiology, Vol. 44, Issue 7, pp. 803-814, (2017) (PubMed).

Ge, Li, Jiang, You, Liu, Zhong, Huang, Xing: "Integration of nondegradable polystyrene and degradable gelatin in a core-sheath nanofibrous patch for pelvic reconstruction." in: International journal of nanomedicine, Vol. 10, pp. 3193-201, (2015) (PubMed).

Saxena, Bujak, Frunza, Dobaczewski, Gonzalez-Quesada, Lu, Gerard, Frangogiannis: "CXCR3-independent actions of the CXC chemokine CXCL10 in the infarcted myocardium and in isolated cardiac fibroblasts are mediated through proteoglycans." in: Cardiovascular research, Vol. 103, Issue 2, pp. 217-27, (2014) (PubMed).

Zhang, Fei, Gao, Liu, Zhang: "The role of CXCR3 in the induction of primary biliary cirrhosis." in: Clinical & developmental immunology, Vol. 2011, pp. 564062, (2011) (PubMed).

Burgess: "Motor control and the role of occupational therapy: past, present, and future." in: The American journal of occupational therapy : official publication of the American Occupational Therapy Association, Vol. 43, Issue 5, pp. 345-8, (1989) (PubMed).

Target Details for CXCR3

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Alternative Name: CXCR3/CD183

Background:

Synonyms: Cd183, Cmkar3, C-X-C chemokine receptor type 3, CXC-R3, CXCR-3, Interferon-inducible protein 1 receptor, IP-1 receptor, Cxcr3

Background: Receptor for the C-X-C chemokine CXCL9, CXCL1 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell chemotaxis response (By similarity). Binds to CCL21.

Gene ID: 12766

UniProt: O88410