CD161 antibody (AA 151-225)
Quick Overview for CD161 antibody (AA 151-225) (ABIN680998)
Target
See all CD161 (KLRB1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 151-225
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Cross-Reactivity
- Human, Rat
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human CD161/NK11
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Isotype
- IgG
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anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 73-188) antibody
KLRB1 Reactivity: Human WB, IP, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibodyKLRB1 Reactivity: Human, Non-Human Primate FACS, WB, IHC (fro) Host: Mouse Monoclonal HP-3G10 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibody (PE)KLRB1 Reactivity: Rat FACS Host: Mouse Monoclonal 10-78 PE
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 67-225) antibodyKLRB1 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 4C6A11 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibodyKLRB1 Reactivity: Rat FACS, WB, IP, IHC (fro), RIA Host: Mouse Monoclonal 10-78 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibody (FITC)KLRB1 Reactivity: Rat FACS Host: Mouse Monoclonal 10-78 FITC
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 73-140) antibodyKLRB1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibodyKLRB1 Reactivity: Rat FACS, WB, IP, IHC (fro), RIA Host: Mouse Monoclonal 10-78 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibody (PE)KLRB1 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal HP-3G10 PE
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 126-225) antibodyKLRB1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2F3 unconjugated
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Application Notes
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WB 1:300-5000
ELISA 1:500-1000 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Expiry Date
- 12 months
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- CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
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Alternative Name
- CD161
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Background
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Synonyms: NKR, CD161, CLEC5B, NKR-P1, NKRP1A, NKR-P1A, hNKR-P1A, Killer cell lectin-like receptor subfamily B member 1, C-type lectin domain family 5 member B, Natural killer cell surface protein P1A, KLRB1
Background: Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells.
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Gene ID
- 3820
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UniProt
- Q12918
Target
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