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PARD3 antibody (AA 1201-1356) (FITC)

The Rabbit Polyclonal anti-PARD3 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect PARD3 in samples from Human.
Catalog No. ABIN681725

Quick Overview for PARD3 antibody (AA 1201-1356) (FITC) (ABIN681725)

Target

See all PARD3 Antibodies
PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Reactivity

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  • 17
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  • 1
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Human

Host

  • 55
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Rabbit

Clonality

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Polyclonal

Conjugate

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This PARD3 antibody is conjugated to FITC

Application

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

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    AA 1201-1356

    Cross-Reactivity

    Human

    Predicted Reactivity

    Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human PARD-3

    Isotype

    IgG
  • Application Notes

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

    Alternative Name

    PARD-3

    Background

    Synonyms: Baz, ASIP, PAR3, PARD-3, PARD3A, SE2-5T2, PPP1R118, SE2-5L16, SE2-5LT1, PAR3alpha, Partitioning defective 3 homolog, PAR-3, Atypical PKC isotype-specific-interacting protein, CTCL tumor antigen se2-5, PAR3-alpha, PARD3, PAR3A

    Background: Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.

    Gene ID

    56288

    UniProt

    Q8TEW0

    Pathways

    Cell-Cell Junction Organization
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