BMX antibody (pTyr40)

Catalog No. ABIN684598

This Rabbit Polyclonal antibody specifically detects BMX in WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Rat.

Quick Overview for BMX antibody (pTyr40) (ABIN684598)

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-BMX Antibody

Binding Specificity: pTyr40

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human ETK around the phosphorylation site of Tyr40

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BMX

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Alternative Name: BMX

Background:

Synonyms: BMX phospho Y40, BMX phospho Try40, BMX p-Y40, BMX p-Try40, p-BMX phospho Y40, BMX/ETK Tyr40, p-ETK Tyr40, Protein tyrosine kinase BMX, PSCTK 2, PSCTK 3, PSCTK2, PSCTK3, Bone marrow tyrosine kinase gene in chromosome X protein, BMX non receptor tyrosine kinase, Cytoplasmic tyrosine protein kinase BMX, Epithelial and endothelial tyrosine kinase, BMX_HUMAN, Cytoplasmic tyrosine-protein kinase BMX, ETK, NTK38, Protein tyrosine kinase BMX, Etk, Etk/Bmx, Tyro8.

Background: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].

Gene ID: 660