COX IV antibody

Catalog No. ABIN687892

This Rabbit Polyclonal antibody specifically detects COX IV in WB, IHC (p) and IF (p). It exhibits reactivity toward Human, Rat, Mouse and Cow.

Quick Overview for COX IV antibody (ABIN687892)

Target: COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

Reactivity: Human, Rat, Mouse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX IV antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-COX IV Antibody

Cross-Reactivity: Cow, Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse COX IV-1

Isotype: IgG

Application Details

Application Notes: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for COX IV

Target: COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

Alternative Name: COX4/COX IV-1

Background:

Synonyms: COX 4, COX 4I1, COX 4I2, COX IV 1, COX IV, COX4 2, COX4, COX4B, COX4I1, COX4I2, COX4L2, COXIV 2, COXIV, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit 4 isoform 1 mitochondrial, Cytochrome C Oxidase Subunit IV, Cytochrome c oxidase subunit IV isoform 1, Cytochrome c oxidase subunit IV isoform 2 lung, dJ857M17.2, MGC72016, COX IV-1, Cox4a Cytochrome c oxidase polypeptide IV.

Background: Cytochrome C Oxidase (COX), which is located in the inner mitochondrial membrane, is the terminal enzyme complex of the mitochondrial electron transport chain. It collects electrons that are transferred from reduced CYTOCHROME C and donates them to molecular oxygen, which is then reduced to water. It is composed of CYTOCHROME A and CYTOCHROME B, two copper atoms, and 13 different protein subunits, three of which are encoded by the mitochondrial DNA and ten others by nuclear DNA.

Molecular Weight: 17kDa

Gene ID: 1327

Pathways: Proton Transport