tau antibody (pSer202, pThr205)

Catalog No. ABIN6932884

The Rabbit Monoclonal anti-tau antibody has been validated for WB, ELISA, IHC, IF, ICC and DB. It is suitable to detect tau in samples from Human.

Quick Overview for tau antibody (pSer202, pThr205) (ABIN6932884)

Target: tau (tau Protein)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This tau antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Dot Blot (DB)

Clone: AH36

Product Details anti-tau Antibody

Binding Specificity: pSer202, pThr205

Specificity: Expressed in neurons.,Detects ~79 kDa.

Cross-Reactivity: Human, Mouse

Purification: Affinity Purified

Immunogen: Synthetic peptide of Human Phospho Tau (Ser202/Thr205)

Isotype: IgG

Application Details

Application Notes:

• WB (1:500)
• ICC/IF (1:500)
• IHC (1:500)
• optimal dilutions for assays should be determined by the user.

Comment:

A 1:500 dilution of ABIN6932884 was sufficient for detection of Tau in 10 μg Baculovirus by dot blot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for tau

Target: tau (tau Protein)

Alternative Name: Tau

Background: Alzheimer's Disease (AD) is the most common neurodegenerative disease, affecting 10 % of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3).

Gene ID: 4137

UniProt: P10636