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CD31 antibody (PE)

The Mouse Monoclonal anti-CD31 antibody has been validated for FACS, IF and T. It is suitable to detect CD31 in samples from Human, Rabbit and Cynomolgus.
Catalog No. ABIN6934746

Quick Overview for CD31 antibody (PE) (ABIN6934746)

Target

See all CD31 (PECAM1) Antibodies
CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reactivity

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Human, Rabbit, Cynomolgus

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This CD31 antibody is conjugated to PE

Application

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Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Clone

JC-70A
  • Specificity

    CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

    No Cross-Reactivity

    Pig (Porcine), Rat (Rattus)

    Purification

    Purified by Protein A/G

    Immunogen

    Membrane preparation of a spleen from a patient with hairy cell leukemia

    Isotype

    IgG1 kappa
  • Application Notes

    Positive Control: Jurkat, CCRF-CEM or K-562 cells. Tonsil, Angiosarcoma.

    Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100 for 30 minutes at RT),Optimal dilution for a specific application should be determined.

    Restrictions

    For Research Use only
  • Concentration

    100 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA and 0.05 % azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Expiry Date

    24 months
  • Target

    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

    Alternative Name

    PECAM1

    Molecular Weight

    ~100kDa (endothelium) and ~130kDa (platelets)'

    Gene ID

    5175

    UniProt

    P16284

    Pathways

    Regulation of Actin Filament Polymerization
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