CD70 antibody
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- Target See all CD70 Antibodies
- CD70 (CD70 Molecule (CD70))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD70 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Coating (Coat), Functional Studies (Func)
- Specificity
- It recognizes a protein of 30 kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant human CD70 protein
- Clone
- TNFS7-1026
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD70 Primary Antibody
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- Application Notes
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Known_Application: ELISA (For coating, order Ab without BSA), Functional Studies (Order Ab without Azide), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Frozen) (1-2 μg/mL for 30 minutes at RT),Optimal dilution for a specific application should be determined.
Positive_Control: Raji cells. Lymph node or tonsil.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- CD70 (CD70 Molecule (CD70))
- Alternative Name
- CD70 (CD70 Products)
- Synonyms
- CD27LG antibody, Cd27l antibody, Tnfsf7 antibody, CD27L antibody, TNFSF7 antibody, CD70 antigen antibody, CD70 molecule antibody, Cd70 molecule antibody, Cd70 antibody, CD70 antibody
- Background
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CD27 ligand (CD27L), CD27LG, Ki24, Surface antigen CD70, Tumor necrosis factor (ligand) superfamily, member 7 (TNFSF7),CD70 / TNFSF7 (Activated T- & B-Lymphocyte Marker)
Cellular localisation: Cell Surface - Molecular Weight
- 30kDa
- Gene ID
- 970, 501497, 715224
- UniProt
- P32970
- Pathways
- Cancer Immune Checkpoints
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