ETS1 antibody (AA 137-230)

Catalog No. ABIN6937200

The Mouse Monoclonal anti-ETS1 antibody has been validated for ELISA and Coat. It is suitable to detect ETS1 in samples from Human.

Quick Overview for ETS1 antibody (AA 137-230) (ABIN6937200)

Target: ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ETS1 antibody is un-conjugated

Application: ELISA, Coating (Coat)

Clone: ETS1-1801

Product Details anti-ETS1 Antibody

Binding Specificity: AA 137-230

Specificity: ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator.The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells.ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human ETS1 fragment (around aa137-230) (exact sequence is proprietary)

Isotype: IgG2b kappa

Application Details

Application Notes:

Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Optimal dilution for a specific application should be determined.

Positive_Control: HepG2 and HeLa cells. Tonsil, Skin, Pancreas, Kidney and Lymphoma.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for ETS1

Target: ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Alternative Name: ETS1

Background: Avian erythroblastosis virus E26 (v ets) oncogene homolog 1, ETS1, EWSR2, p54, v-ets erythroblastosis virus E26 oncogene homolog 1,ETS1 (Marker of Tumor Metastasis)
Cellular localisation: Nuclear

Molecular Weight: 54kDa

Gene ID: 2113, 369438

UniProt: P14921