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GATA3 antibody (AA 357-436)

GATA3 Reactivity: Human IHC (f) Host: Mouse Monoclonal GATA3-2442 unconjugated
Catalog No. ABIN6937301
  • Target See all GATA3 Antibodies
    GATA3 (GATA Binding Protein 3 (GATA3))
    Binding Specificity
    • 33
    • 16
    • 15
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 357-436
    Reactivity
    • 113
    • 83
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    Human
    Host
    • 104
    • 29
    • 2
    • 1
    Mouse
    Clonality
    • 94
    • 42
    Monoclonal
    Conjugate
    • 73
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This GATA3 antibody is un-conjugated
    Application
    • 89
    • 45
    • 27
    • 27
    • 27
    • 19
    • 19
    • 17
    • 10
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificity
    GATA-3 is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. GATA-3 expression is primarily seen in breast and urothelial carcinomas.'Therefore, GATA3 antibody can be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility.
    Cross-Reactivity (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant fragment of human GATA3 protein (around aa 357-436) (exact sequence is proprietary)
    Clone
    GATA3-2442
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product GATA3 Primary Antibody
  • Application Notes

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: MCF-7 or T47D cells. Breast or Bladder Carcinoma.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    GATA3 (GATA Binding Protein 3 (GATA3))
    Alternative Name
    GATA3 (GATA3 Products)
    Background
    GATA3, GATA binding protein-3, GATA-binding factor 3, GATA3, HDR, HDRS, Transacting T-cell-specific transcription factor GATA-3,GATA-3 (Breast and Urothelial Marker)
    Cellular localisation: Nuclear
    Molecular Weight
    50kDa
    Gene ID
    2625, 524134
    UniProt
    P23771
    Pathways
    Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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