GATA3 antibody (AA 357-436)
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- Target See all GATA3 Antibodies
- GATA3 (GATA Binding Protein 3 (GATA3))
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Binding Specificity
- AA 357-436
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This GATA3 antibody is un-conjugated
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Application
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificity
- GATA-3 is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. GATA-3 expression is primarily seen in breast and urothelial carcinomas.'Therefore, GATA3 antibody can be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment of human GATA3 protein (around aa 357-436) (exact sequence is proprietary)
- Clone
- GATA3-2442
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product GATA3 Primary Antibody
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- Application Notes
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7 or T47D cells. Breast or Bladder Carcinoma.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- GATA3 (GATA Binding Protein 3 (GATA3))
- Alternative Name
- GATA3 (GATA3 Products)
- Background
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GATA3, GATA binding protein-3, GATA-binding factor 3, GATA3, HDR, HDRS, Transacting T-cell-specific transcription factor GATA-3,GATA-3 (Breast and Urothelial Marker)
Cellular localisation: Nuclear - Molecular Weight
- 50kDa
- Gene ID
- 2625, 524134
- UniProt
- P23771
- Pathways
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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