ITGB1 antibody
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- Target See all ITGB1 Antibodies
- ITGB1 (Integrin beta 1 (ITGB1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ITGB1 antibody is un-conjugated
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Application
- ELISA, Coating (Coat)
- Specificity
- Recognizes CD29. Binds to the cell membrane of T- and B- lymphocytes, monocytes, platelets, fibroblasts, endothelial cells, mast cells and smooth muscle cells. CD29 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin.
- No Cross-Reactivity
- Mouse (Murine), Rat (Rattus)
- Cross-Reactivity (Details)
- Human. Does not react with Mouse or Rat.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Purified human beta 1 integrin from HT1080 fibrosarcoma cell extract.
- Clone
- 12G10
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product ITGB1 Primary Antibody
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- Application Notes
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Known_Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA) Optimal dilution for a specific application should be determined.
Positive_Control: HT1080 whole cell lysate. HeLa cell line.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- ITGB1 (Integrin beta 1 (ITGB1))
- Alternative Name
- ITGB1 (ITGB1 Products)
- Background
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Fibrinogen Receptor beta subunit, FNRB, Glycoprotein IIa (GPIIA), Integrin beta-1 (ITGB1), integrin VLA-4 beta subunit, MDF2, MSK12, Very Late Activation Protein beta Polypeptide, VLA-4 subunit beta, VLA-BETA, VLAB,CD29 (Stem Cell Marker)
Cellular localisation: Cell Surface - Molecular Weight
- 110kDa (non-reduced) & 130kDa (reduced)
- Gene ID
- 3688, 643813
- UniProt
- P05556
- Pathways
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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