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ITGB1 antibody

ITGB1 Reactivity: Human ELISA, Coat Host: Mouse Monoclonal 12G10 unconjugated
Catalog No. ABIN6937596
  • Target See all ITGB1 Antibodies
    ITGB1 (Integrin beta 1 (ITGB1))
    Reactivity
    • 207
    • 92
    • 76
    • 21
    • 18
    • 18
    • 17
    • 10
    • 8
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 150
    • 69
    • 13
    • 6
    • 4
    • 1
    Mouse
    Clonality
    • 139
    • 100
    • 1
    Monoclonal
    Conjugate
    • 108
    • 22
    • 21
    • 14
    • 9
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This ITGB1 antibody is un-conjugated
    Application
    • 118
    • 115
    • 70
    • 55
    • 33
    • 27
    • 27
    • 26
    • 26
    • 18
    • 12
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Coating (Coat)
    Specificity
    Recognizes CD29. Binds to the cell membrane of T- and B- lymphocytes, monocytes, platelets, fibroblasts, endothelial cells, mast cells and smooth muscle cells. CD29 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin.
    No Cross-Reactivity
    Mouse (Murine), Rat (Rattus)
    Cross-Reactivity (Details)
    Human. Does not react with Mouse or Rat.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Purified human beta 1 integrin from HT1080 fibrosarcoma cell extract.
    Clone
    12G10
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product ITGB1 Primary Antibody
  • Application Notes

    Known_Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA) Optimal dilution for a specific application should be determined.

    Positive_Control: HT1080 whole cell lysate. HeLa cell line.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    ITGB1 (Integrin beta 1 (ITGB1))
    Alternative Name
    ITGB1 (ITGB1 Products)
    Background
    Fibrinogen Receptor beta subunit, FNRB, Glycoprotein IIa (GPIIA), Integrin beta-1 (ITGB1), integrin VLA-4 beta subunit, MDF2, MSK12, Very Late Activation Protein beta Polypeptide, VLA-4 subunit beta, VLA-BETA, VLAB,CD29 (Stem Cell Marker)
    Cellular localisation: Cell Surface
    Molecular Weight
    110kDa (non-reduced) & 130kDa (reduced)
    Gene ID
    3688, 643813
    UniProt
    P05556
    Pathways
    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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