TGF-beta antibody
Quick Overview for TGF-beta antibody (ABIN6938530)
Target
See all TGF-beta (TGFb) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This MAb recognizes TGF beta 1, 2 and 3. Three TGF's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.
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Cross-Reactivity (Details)
- Human. Monkey. Cow. Dog. Mouse. Rat. Hamster.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Bovine TGF-beta2 protein
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Isotype
- IgG1 kappa
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Application Notes
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Known_Application: Cytokine Neutralization (Order Ab without BSA/Azide), Functional Assay (Order Ab without BSA/Azide), ELISA (0.1-0.4 μg/mL - Detection, 2-8 μg/mL - Capture), Immunofluorescence (8-25 μg/mL), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: Salivary gland carcinoma.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Preservative
- Azide free
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Storage
- -20 °C,-80 °C
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Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Expiry Date
- 24 months
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- TGF-beta (TGFb)
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Alternative Name
- TFGB
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Background
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ARVD, BSC 1 cell growth inhibitor, CED, Cetermin, Diaphyseal dysplasia 1 (DPD1), Glioblastoma derived T cell suppressor factor (G TSF), Latency-associated peptide (LAP), Polyergin, Transforming growth factor beta 1 (TGF beta1 or TGFB1), TGF beta2 (TGFB2), TGF beta3 (TGFB3), TGFbeta (TGFB),TGF-beta (Transforming Growth Factor beta)
Cellular localisation: Cytoplasm and extracellular (secreted) -
Molecular Weight
- 13kDa
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Gene ID
- 7040, 7042, 7043
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UniProt
- P01137, P10600, P61812
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Pathways
- EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
Target
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