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TGF-beta antibody

This anti-TGF-beta antibody is a Mouse Monoclonal antibody detecting TGF-beta in WB, Neut, ELISA, Func, D, ELISA (Capture) and IF. Suitable for Cow.
Catalog No. ABIN6938530

Quick Overview for TGF-beta antibody (ABIN6938530)

Target

See all TGF-beta (TGFb) Antibodies
TGF-beta (TGFb)

Reactivity

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Cow

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This TGF-beta antibody is un-conjugated

Application

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Western Blotting (WB), Neutralization (Neut), ELISA, Functional Studies (Func), Detection (D), ELISA (Capture), Immunofluorescence (IF)

Clone

1D11-16-8
  • Specificity

    This MAb recognizes TGF beta 1, 2 and 3. Three TGF's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.

    Cross-Reactivity (Details)

    Human. Monkey. Cow. Dog. Mouse. Rat. Hamster.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Bovine TGF-beta2 protein

    Isotype

    IgG1 kappa
  • Application Notes

    Known_Application: Cytokine Neutralization (Order Ab without BSA/Azide), Functional Assay (Order Ab without BSA/Azide), ELISA (0.1-0.4 μg/mL - Detection, 2-8 μg/mL - Capture), Immunofluorescence (8-25 μg/mL), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: Salivary gland carcinoma.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Preservative

    Azide free

    Storage

    -20 °C,-80 °C

    Storage Comment

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Expiry Date

    24 months
  • Target

    TGF-beta (TGFb)

    Alternative Name

    TFGB

    Background

    ARVD, BSC 1 cell growth inhibitor, CED, Cetermin, Diaphyseal dysplasia 1 (DPD1), Glioblastoma derived T cell suppressor factor (G TSF), Latency-associated peptide (LAP), Polyergin, Transforming growth factor beta 1 (TGF beta1 or TGFB1), TGF beta2 (TGFB2), TGF beta3 (TGFB3), TGFbeta (TGFB),TGF-beta (Transforming Growth Factor beta)
    Cellular localisation: Cytoplasm and extracellular (secreted)

    Molecular Weight

    13kDa

    Gene ID

    7040, 7042, 7043

    UniProt

    P01137, P10600, P61812

    Pathways

    EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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