YBX1 antibody
-
- Target See all YBX1 Antibodies
- YBX1 (Y Box Binding Protein 1 (YBX1))
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This YBX1 antibody is un-conjugated
-
Application
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificity
- The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Y-box binding protein-1 (YBX1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus, YBX1 protein orchestrates transcription of proliferation-related genes, whereas in the cytoplasm it associates with mRNA and directs translation. In human tumor entities, such as breast, lung and prostate cancer, cellular YBX1 expression indicates poor clinical outcome, suggesting that YBX1 is an attractive marker to predict patients' prognosis.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant human full-length YBX1 protein
- Clone
- YBX1-2430
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product YBX1 Primary Antibody
-
-
- Application Notes
-
Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7, HEK293 or PC12 cells. Prostate, Breast or Lung Carcinoma.
- Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
-
- Target
- YBX1 (Y Box Binding Protein 1 (YBX1))
- Alternative Name
- YBX1 (YBX1 Products)
- Synonyms
- BP-8 antibody, CSDA2 antibody, CSDB antibody, DBPB antibody, MDR-NF1 antibody, NSEP-1 antibody, NSEP1 antibody, YB-1 antibody, YB1 antibody, Byb1 antibody, Cbfa antibody, Dbpb antibody, Ef1a antibody, Msy1 antibody, Nsep1 antibody, Yb1 antibody, bp-8 antibody, csda2 antibody, csdb antibody, dbpb antibody, frgy1 antibody, mdr-nf1 antibody, nsep-1 antibody, nsep1 antibody, yb1 antibody, 1700102N10Rik antibody, C79409 antibody, EF1A antibody, MSY1 antibody, dbpB antibody, mYB-1a antibody, nuclease sensitive element binding protein 1 antibody, Y-box binding protein 1 antibody, Y box binding protein 1 antibody, Y-box binding protein 1 S homeolog antibody, nuclease-sensitive element-binding protein 1 antibody, Y box protein 1 antibody, nsep1 antibody, YBX1 antibody, Ybx1 antibody, ybx1.S antibody, LOC479011 antibody
- Background
-
BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1,YBX1 / Y-box Binding Protein 1 / YB-1 (Tumor Biomarker)
Cellular localisation: Cytoplasmic and Nuclear - Molecular Weight
- 36kDa
- Gene ID
- 4904, 473583
- UniProt
- P67809
- Pathways
- Regulation of Muscle Cell Differentiation
-