BAFF antibody

Catalog No. ABIN6939086

This anti-BAFF antibody is a Mouse Monoclonal antibody detecting BAFF in ELISA and Coat. Suitable for Human.

Quick Overview for BAFF antibody (ABIN6939086)

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BAFF antibody is un-conjugated

Application: ELISA, Coating (Coat)

Clone: C257-1638

Product Details anti-BAFF Antibody

Specificity: BAFF/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31 kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN- BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).

Cross-Reactivity (Details): Human,

Purification: 200ug/ml of Ab Purified from rabbit anti-serum by Protein A.

Immunogen: Purified recombinant human CD257 protein

Isotype: IgG1

Application Details

Application Notes:

Positive Control: Jurkat cells. Tonsil and lymph node.

Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Expiry Date: 24 months

Target Details for BAFF

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Alternative Name: TNFSF13B

Background: ApoL related ligand TALL 1, B lymphocyte stimulator, B-cell-activating factor, BAFF, BLyS, CD257, Dendritic cell-derived TNF-like molecule, DTL, PRO738, TALL-1, THANK, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13b, Tumor necrosis factor ligand superfamily member 20, ZTNF4,CD257 / BAFF / TNFSF13B
Cellular localisation: Cell surface and cytoplasmic

Molecular Weight: 31kDa (Monomer)

Gene ID: 10673, 525157

UniProt: Q9Y275

Pathways: NF-kappaB Signaling, Production of Molecular Mediator of Immune Response