L1CAM antibody
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- Target See all L1CAM Antibodies
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This L1CAM antibody is un-conjugated
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Application
- ELISA, Coating (Coat)
- Specificity
- Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius), 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs), and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
- Purification
- Purified by Protein A/G
- Immunogen
- Homogenous suspension of 16-week human fetal brain
- Clone
- UJ127
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product L1CAM Primary Antibody
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anti-L1 Cell Adhesion Molecule (L1CAM) (AA 151-200) antibody
L1CAM Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 20-197) antibodyL1CAM Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 5C6A10 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyL1CAM Reactivity: Human, Dog, Monkey WB, FACS, IF Host: Mouse Monoclonal 2G9 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyL1CAM Reactivity: Human, Monkey WB, FACS Host: Mouse Monoclonal 2A5 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 1143-1257) antibodyL1CAM Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 526-690) antibodyL1CAM Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 995-1119) antibodyL1CAM Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 1101-1257) antibodyL1CAM Reactivity: Human, Rat FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (Ser727) antibodyL1CAM Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (C-Term) antibodyL1CAM Reactivity: Human WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Positive Control: Neuroblastomas or Schwannomas.
Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
- Alternative Name
- L1CAM (L1CAM Products)
- Molecular Weight
- 220-240kDa
- Gene ID
- 3897
- UniProt
- P32004
- Pathways
- Synaptic Membrane
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