RNLS antibody (AA 34-235)

Catalog No. ABIN6940382

This anti-RNLS antibody is a Mouse Monoclonal antibody detecting RNLS in ELISA and Coat. Suitable for Human.

Quick Overview for RNLS antibody (AA 34-235) (ABIN6940382)

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RNLS antibody is un-conjugated

Application: ELISA, Coating (Coat)

Clone: RNLS-1940

Product Details anti-RNLS Antibody

Binding Specificity: AA 34-235

Purification: Purified by Protein A/G

Immunogen: Recombinant human RNLS protein fragment (around aa 34-235) (exact sequence is proprietary)

Isotype: IgG2b kappa

Application Details

Application Notes:

Positive Control: 293T cells. Heart or Kidney.

Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for RNLS

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Alternative Name: RNLS

Background: Renalase is a 342 amino acid FAD-dependent amine oxidase that is highly expressed in kidney and is expressed at a lower level in heart, skeletal muscle and small intestine. Renalase is secreted in the blood by the kidney and it is thought to regulate cardiac function and systemic blood pressure. It is also suggested that Renalase functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. Individuals with chronic kidney disease and end-stage renal disease have markedly reduced levels of plasma Renalase than healthy individuals. Infusion of Renalase in animal models causes decrease in heart rate, cardiac contractility and blood pressure. Two isoforms of Renalase exist due to alternative splicing events.

Molecular Weight: 38kDa

Gene ID: 55328

UniProt: Q5VYX0