Small Cell Lung Cancer (SCLC) antibody

Catalog No. ABIN6941387

Product Details

Target: Small Cell Lung Cancer (SCLC)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: This MAb reacts with a membrane-associated protein present in normal and malignant neuroendocrine tissues including small cell lung cancer (SCLC). It stains neural and a variable number of endocrine tissues and in the lung it reacts preferentially with SCLC and carcinoids. Its epitope is destroyed during formalin fixation. This antibody was categorized during the First International Workshop on Small Cell Lung Cancer Antigens held in London in April 1987. There are two major types of Lung Carcinoma: non-small cell, which accounts for 80 % of all cases, and small cell, which accounts for roughly 20 % of all lung cancers reported. The lung continues to be a customary place for cancer migration from tumors elsewhere in the body. Treatment depends on the specific cell type of the cancer, level of progression and status of the individual patient.

Purification: Purified by Protein A/G

Immunogen: Lung Cancer-associated antigen isolated from small cell lung carcinoma-derived cell line

Clone: MOC-52

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: Human small cell lung carcinoma, adrenal gland.

Known Application: Immunofluorescence (0.5-1 μg/mL), Immunocytochemistry (Frozen) (0.5-1.0 μg/mL for 30 minutes at RT), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details

Target: Small Cell Lung Cancer (SCLC)

Alternative Name: Small Cell Lung Carcinoma Antigen (SCLC Marker)

Molecular Weight: 145kDa