COX6A1 antibody (AA 25-109) (Cy7)

Catalog No. ABIN6942619

The Rabbit Polyclonal anti-COX6A1 antibody has been validated for IF (cc) and IF (p). It is suitable to detect COX6A1 in samples from Mouse.

Quick Overview for COX6A1 antibody (AA 25-109) (Cy7) (ABIN6942619)

Target: COX6A1 (Cytochrome C Oxidase Subunit VIa Polypeptide 1 (COX6A1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX6A1 antibody is conjugated to Cy7

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-COX6A1 Antibody (Cy7)

Binding Specificity: AA 25-109

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COX6A1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for COX6A1

Target: COX6A1 (Cytochrome C Oxidase Subunit VIa Polypeptide 1 (COX6A1))

Alternative Name: COX6A1

Background:

Synonyms: COX VIa L, COX VIa-L, COX6A, COX6A1, COX6AL, CX6A1_HUMAN, Cytochrome c oxidase polypeptide VIa liver, Cytochrome c oxidase polypeptide VIa-liver, Cytochrome c oxidase subunit 6A1, Cytochrome c oxidase subunit 6A1 mitochondrial, Cytochrome C oxidase subunit VIa homolog, Cytochrome c oxidase subunit VIA liver, Cytochrome c oxidase subunit VIa polypeptide 1, Cytochrome c oxidase subunit VIA-liver, MGC104500, mitochondrial.

Background: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66 % amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented. [provided by RefSeq, Jul 2008]

Gene ID: 1337

UniProt: P12074