Doublecortin antibody

Catalog No. ABIN6943114

The Rabbit Monoclonal anti-Doublecortin antibody is suitable to detect Doublecortin in samples from Human, Mouse and Rat. It has been validated for WB and FACS.

Quick Overview for Doublecortin antibody (ABIN6943114)

Target: Doublecortin (DCX)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Doublecortin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 7C4

Product Details anti-Doublecortin Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Human Doublecortin aa 250 to the C-terminus

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Doublecortin

Target: Doublecortin (DCX)

Alternative Name: Doublecortin

Background:

Synonyms: Neuronal migRation protein doublecortin, Doublin, Lissencephalin-X, Lis-X, DCX

Background: Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.

Gene ID: 1641

UniProt: O43602