F11R antibody

Catalog No. ABIN6943391

This anti-F11R antibody is a Rabbit Monoclonal antibody detecting F11R in WB, IHC (p) and IF (cc). Suitable for Human, Mouse and Rat.

Quick Overview for F11R antibody (ABIN6943391)

Target: F11R (F11 Receptor (F11R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This F11R antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 7E1F

Product Details anti-F11R Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Human Junctional Adhesion Molecule 1 between 28-241 amino acids

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: F11R

Background:

Synonyms: Junctional adhesion molecule A, Junctional adhesion molecule 1, Platelet F11 receptor, Platelet adhesion molecule 1, CD321, JAM-A, JAMA, JAM-1, JAM1, PAM-1, F11R

Background: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Gene ID: 50848

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization