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NQO1 antibody (AA 201-274) (Biotin)

NQO1 Reactivity: Human, Mouse WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN6944312
  • Target See all NQO1 Antibodies
    NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
    Binding Specificity
    • 16
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-274
    Reactivity
    • 68
    • 32
    • 31
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 59
    • 7
    • 2
    • 2
    Rabbit
    Clonality
    • 54
    • 16
    Polyclonal
    Conjugate
    • 38
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NQO1 antibody is conjugated to Biotin
    Application
    • 52
    • 24
    • 14
    • 14
    • 12
    • 11
    • 9
    • 8
    • 7
    • 6
    • 4
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse NQO1
    Isotype
    IgG
    Top Product
    Discover our top product NQO1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
    Alternative Name
    NQO1 (NQO1 Products)
    Background

    Synonyms: Azoreductase, Cytochrome b 5 reductase, DHQU, DIA 4, DIA4, Diaphorase (NADH/NADPH) (cytochrome b 5 reductase), Diaphorase (NADH/NADPH) (cytochrome b-5 reductase), Diaphorase (NADH/NADPH) (cytochrome b-5 reductase), Diaphorase (NADH/NADPH), Diaphorase 4, Dioxin inducible 1, DT diaphorase, DT-diaphorase, DTD, Menadione reductase, NAD(P)H dehydrogenase [quinone] 1, NAD(P)H dehydrogenase quinone 1, NAD(P)H menadione oxidoreductase 1 dioxin inducible, NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1, NAD(P)H:menadione oxidoreductase 1, NAD(P)H:Quinone acceptor oxidoreductase type 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxireductase, NMOR 1, NMOR I, NMOR1, NMORI, NQO 1, NQO1, NQO1_HUMAN, Phylloquinone reductase, Phylloquinone reductase, QR 1, QR1, Quinone reductase 1, Quinone reductase 1.

    Background: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

    Gene ID
    18104
    UniProt
    Q64669
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